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Table 2 Analysis of relationships between E-cadherin, Slug and GSK3β expression with β-catenin expression in IDCs.

From: Expression analysis of E-cadherin, Slug and GSK3β in invasive ductal carcinoma of breast

Parameter Total Cases (N) E-Cad (Mem) E-Cad (Cyto) Slug (Nucl) Gsk3β (Nucl) Gsk3β (Cyto)
   - + P - + P - + P - + P - + P
  98 53 45   46 52   65 33   64 34   52 46  
β-catenin (Mem.)                 
Positive 33 9 24 .0001*1 12 21 .199 16 17 0.012*3 19 14 0.270 19 14 0.669
Negative 65 44 21   34 31   49 16   45 20   33 32  
β-catenin (Cyto.)                 
Positive 42 20 22 0.309 18 24 0.543 21 21 0.005*4 24 18 0.198 17 25 0.070
Negative 56 33 23   28 28   44 12   40 16   35 21  
β-catenin (Nucl.)                 
Positive 47 25 22 1.000 17 30 0.046*2 23 24 0.001*5 28 19 0.292 20 27 0.068
Negative 51 28 23   29 22   42 9   36 15   32 19  
  1. Abbreviations: E-cad, E-cadherin; Cyto, Cytoplasmic; Nucl, Nuclear and Mem, Membrane.*1 β-cat (Mem) - /E-cad (Mem) - : p = 0.0001; OR = 5.59 [95% C.I = 2.21-14.1]; * 2 β-cat (Nucl) + /E-cad (Cyto) + : p = 0.046; OR = 2.33 [95% CI = 1.03-5.25]; * 3 β-cat (Mem) - /Slug (Nucl) + : p = 0.012; OR = 3.25 [95% CI = 1.34-7.89]; * 4 β-cat (Cyto) + /Slug (Nucl) + : p = 0.005; OR = 3.67 [95% C.I = 1.53-8.83]; * 5 β-cat (Nucl) + /Slug (Nucl) + : p = 0.001; OR = 4.87 [95% C.I = 1.94-12.21].