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Table 4 Univariate survival analysis of anthracycline- and CMF-treated subgroups, N = 99 and N = 324*

From: Tumor tissue levels of Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) and outcome following adjuvant chemotherapy in premenopausal lymph node-positive breast cancer patients: A retrospective study

  

DFS

 

OS

 
  

HR (95% CI)

P

HR (95% CI)

P

Anthracycline-treated patients

TIMP-1

(continuous variable)

1.66 (0.96-2.85)

0.07

3.52 (1.54-8.06)

0.003

 

TIMP-1

(high vs. low)

1.52 (0.88-2.63)

0.13

2.53 (1.19-5.39)

0.02

CMF-treated patients

TIMP-1

(continuous variable)

1.12 (0.84-1.51)

0.44

1.22 (0.82-1.81)

0.32

 

TIMP-1

(high vs. low)

1.15 (0.82-1.61)

0.42

1.44 (0.91-2.29)

0.12

  1. * Analyses stratified for hormone receptor status, nodal status and RT on the axilla.