Anthracycline-treatment
|
TIMP-1 low vs. all untreated
|
0.71 (0.42-1.19)
|
0.19
|
|
TIMP-1 high vs. all untreated
|
0.97 (0.60-1.57)
|
0.90
|
CMF-treatment
|
TIMP-1 low vs. all untreated
|
0.48 (0.33-0.69)
|
<0.001
|
|
TIMP-1 high vs. all untreated
|
0.57 (0.41-0.81)
|
0.001
|
Age
|
41-55 years vs. ≤ 40 years
|
0.63 (0.49-0.81)
|
<0.001
|
Tumor size
|
Stage 2 (> 2 cm) vs. stage 1 (≤ 2 cm)
|
1.80 (1.33-2.45)
|
<0.001
|
|
Stage 3 (>5 cm or chest wall/skin involvement) vs. stage 1 (≤ 2 cm)
|
1.86 (1.26-2.74)
| |
Grade
|
Unknown vs. poor
|
0.83 (0.61-1.11)
|
0.08
|
|
Well/moderate vs. poor
|
0.69 (0.49-0.98)
| |