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Table 3 The correlation between aberrant expression level of the studied markers and the clinicopathological features of the patients

From: Clinical significance of altered nm23-H1, EGFR, RB and p53 expression in bilharzial bladder cancer

Parameter nm23-H1
IHC(25)
nm23-H1
RNA (19)
EGFR
IHC(39)
EGFR
RNA (32)
Rb
IHC(34)
P53
IHC(21)
Age(mean ± SD) 50.2 ± 11 54.o ± 8.6 51.7 ± 11 48.5 ± 10.2 49.5 ± 11.4 53.9 ± 11.3
p value 0.41 0.63 0.73 0. 41 0.144 0.175
Sex       
Male (42) 19 13 28 25 22 17
Female (17) 6 4 11 7 12 4
p value 0.48 0.42 0.88 0.62 0.2 0.22
Pathology:       
SCC 14 9 16 9 16 7
TCC 10 8 20 20 16 12
AC 1 2 3 3 2 2
P value 0.536 0.661 0.21 0.365 0.85 0.36
Grade:       
I 1 2 3 3 4 0
II 17 15 25 20 22 16
III 7 2 11 9 8 5
P value 0.916 0.713 1.0 0.785 0.71 0.224
Stage:       
p3a 15 4 26 17 25 17
p3b 9 10 7 9 6 2
p4 1 5 6 6 3 2
P value 0.13 0.02 0.003 0.01 0.023 0.004
Lymp nodes:       
Positive 9 6 8 4 4 6
Negative 16 13 31 28 30 15
P value <0.0001 <0.0001 0.31 0.431 0.216 0.02
Recurrence:       
Negative 16 15 26 24 23 13
Positive 9 4 13 8 11 8
P value 0.43 0.51 0.06 0.003 0.72 0.347
Metastasis:       
Negative 20 15 31 23 30 13
Positiv e 5 4 8 9 4 8
P value 0.75 0.51 0.78 0.511 0.026 <0.0001
  1. SCC = Squamous Cell Carcinoma; TCC = Transitional Cell Carcinoma; Adeno = Adenocarcinoma