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Table 2 Correlation between the clinicopathological features and expression of Cripto-1

From: Cripto-1 overexpression is involved in the tumorigenesis of nasopharyngeal carcinoma

   Cripto-1  
Clinicopathological
variables
Cases
(n = 37)
positive (%) negative (%) pvalue
   n = 20 n = 17  
Gender     0.627
   Male 26 14 (53.8) 12 (46.2)  
   Female 11 6 (54.5) 5 (45.5)  
Age(years) a     0.540
   ≤ 49 21 11(52.4) 10 (47. 6)  
   >49 16 9 (56.3) 7 (43.7)  
Pathological classification(WHO)     0.062
Type I-II 17 12(70.6) 5 (29.4)  
Type III 20 8 (40.0) 12 (60.0)  
Depth of invasion
T classification
    0.474
   T1-2 27 14(51.9) 13 (48.1)  
   T3-4 10 6(60) 4(40)  
Lymph node metastasis
N classification
    0.034c
N0 9 2 (22.2) 7 (77.8)  
N1-3 28 18(64.3) 10 (35.7)  
Distant metastasis     0.036c
   Yes 5 5(100.0) 0(0.0)  
   No 32 15 (48.4) 17(51.6)  
Clinical Staging b     0.007c
I-II 15 4 (26.7) 11 (73.3)  
III-IV 22 16(72.7) 6(27.3)  
  1. agrouping of age was performed according to median.
  2. bclinical staging was performed according to 1992 Fuzhou NPC staging system of China.
  3. c statistical significance (p < 0.05)