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Table 2 Correlation between the clinicopathological features and expression of Cripto-1

From: Cripto-1 overexpression is involved in the tumorigenesis of nasopharyngeal carcinoma

  

Cripto-1

 

Clinicopathological

variables

Cases

(n = 37)

positive (%)

negative (%)

pvalue

  

n = 20

n = 17

 

Gender

   

0.627

   Male

26

14 (53.8)

12 (46.2)

 

   Female

11

6 (54.5)

5 (45.5)

 

Age(years) a

   

0.540

   ≤ 49

21

11(52.4)

10 (47. 6)

 

   >49

16

9 (56.3)

7 (43.7)

 

Pathological classification(WHO)

   

0.062

Type I-II

17

12(70.6)

5 (29.4)

 

Type III

20

8 (40.0)

12 (60.0)

 

Depth of invasion

T classification

   

0.474

   T1-2

27

14(51.9)

13 (48.1)

 

   T3-4

10

6(60)

4(40)

 

Lymph node metastasis

N classification

   

0.034c

N0

9

2 (22.2)

7 (77.8)

 

N1-3

28

18(64.3)

10 (35.7)

 

Distant metastasis

   

0.036c

   Yes

5

5(100.0)

0(0.0)

 

   No

32

15 (48.4)

17(51.6)

 

Clinical Staging b

   

0.007c

I-II

15

4 (26.7)

11 (73.3)

 

III-IV

22

16(72.7)

6(27.3)

 
  1. agrouping of age was performed according to median.
  2. bclinical staging was performed according to 1992 Fuzhou NPC staging system of China.
  3. c statistical significance (p < 0.05)
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