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Table 1 Clinico-pathological characteristics of the patients.

From: Histological evaluation of AMPK signalling in primary breast cancer

Parameter Cohort 1 [n (%)] Cohort 2 [n (%)] P
N 117 237  
Menopausal status at diagnosis    
   Pre- and peri-menopausal 62 (53) 56 (24) < 0.001*
   Post-menopausal 55 (47) 181 (76)  
Age (years)    
   Median (range) 51 (34-76) 62 (28-89) < 0.001~
Tumour size (cm)    
   ≤ 2 61 (57) 88 (37) < 0.001*
   > 2 46 (43) 148 (63)  
Number of positive lymph nodes    
   0 48 (41) 127 (54) 0.032*
0.540*
   1-3 48 (41) 74 (31)  
   > 3 21 (18) 36 (15)  
Histological grade    
   1 12 (10) 34 (14) 0.399*
0.425*
   2 43 (38) 91 (39)  
   3 59 (52) 110 (47)  
Adjuvant therapy    
   Endocrine therapy 18 (16) 59 (27) N/A
   Chemotherapy and/or Radiotherapy 0 (0) 54 (24)  
   Endocrine + Chemotherapy 12 (10) 10 (4)  
   Endocrine + Radiotherapy 45 (38) 70 (31)  
   Endocrine + Chemo + Radiotherapy 42 (36) 31 (14)  
Follow up (months)    
   Median (range) 73 (9-122) 60 (1-120) < 0.001~
  1. Notes: *2-sided Fisher's Exact Test; ~ Mann-Whitney U-test; first row versus summation of all other rows; last row versus summation of all other rows.