Table 3 The known groups comparison before treatment

EORTC QLQ-C30

Functioning scores**

Physical functioning

75.3 (15.8)

55.1 (23.5)

< 0.0001

Role functioning

(19.5) 77.7

60.3 (27.3)

0.001

Emotional functioning

67.1 (25.1)

53.4 (26.6)

0.008

Cognitive functioning

96.4 (10.9)

90.6 (14.7)

0.009

Social functioning

78.6 (16.7)

(25.2)71.8

0.26

Global quality of life

45.7 (11.8)

39.2 (10.5)

0.007

Symptom scores***

Fatigue

36.0 (24.4)

56.8 (27.1)

< 0.0001

Nausea & vomiting

10.0 (22.3)

24.2 (28.1)

0.001

Pain

30.4 (24.1)

52.8 (28.3)

< 0.0001

Dyspnea

6.0 (14.5)

9.6 (20.9)

0.51

Insomnia

27.3 (33.4)

46.0 (35.4)

0.006

Appetite loss

34.0 (38.9)

54.0 (37.6)

0.007

Constipation

10.6 (24.6)

27.7 (37.6)

0.009

Diahrea

5.3 (15.5)

5.5 (16.8)

0.91

Financial difficulties

80.8 (30.0)

72.8 (36.6)

0.26

QLQ-STO22 scores***

Dysphagia

15.6 (20.6)

29.1 (28.3)

0.01

Stomach area pain

25.0 (24.4)

38.3 (24.4)

0.005

Reflux

20.3 (20.1)

30.3 (24.6)

0.03

Eating restrictions

29.9 (14.9)

33.3 (16.1)

0.44

Anxiety

50.3 (27.6)

65.3 (29.4)

0.01

Dry mouth

29.2 (35.1)

52.3 (35.3)

0.001

Taste problem

20.4 (32.5)

31.2 (33.6)

0.06

Body image

20.9 (24.7)

26.6 (33.5)

0.73

Hair loss

17.3 (33.4)

18.8 (27.2)

0.51