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Figure 4 | BMC Cancer

Figure 4

From: Epidermal Growth Factor Receptor (EGFR) gene copy number (GCN) correlates with clinical activity of irinotecan-cetuximab in K-RAS wild-type colorectal cancer: a fluorescence in situ (FISH) and chromogenic in situ hybridization (CISH) analysis

Figure 4

Receiver operating characteristics (ROC) analysis based on mean CISH EGFR gene copy number with response to cetuximab therapy as end point. In this model sensitivity was 51.5% (95% CI 33.6–69.2) and specificity was 100% (95% CI 69–100). AUC was 0.77, p = 0.002.

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