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Figure 1 | BMC Cancer

Figure 1

From: Epidermal Growth Factor Receptor (EGFR) gene copy number (GCN) correlates with clinical activity of irinotecan-cetuximab in K-RAS wild-type colorectal cancer: a fluorescence in situ (FISH) and chromogenic in situ hybridization (CISH) analysis

Figure 1

Receiver operating characteristics (ROC) analysis based on mean FISH EGFR gene copy number with response to cetuximab therapy as end point. In this model sensitivity was 96.3% (95% CI 81 – 99.4) and specificity was 90% (95% CI 55.5–98.3). AUC was 0.95, p = 0.0003.

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