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Table 1 Histopathological analysis of the ventral and dorsolateral prostate lobes of SV-40 Tag rats fed control AIN-76A diet

From: Characterization of SV-40 Tag rats as a model to study prostate cancer

  

Histopathological

Grades

Histopathological

Grades

Age

n

(Ventral Prostate)

(Dorsolateral prostate)

1 day

2

1, 1

1, 1

1 week

4

1, 1, 1, 1

1, 1, 1, 1

2 weeks

6

2, 2, 2, 2, 2, 2

1, 1, 2, 2, 2, 2

3 weeks

2

2, 2

2, 2

4 weeks

2

3, 3

2, 2

5 weeks

4

2, 2, 3, 3

1, 2, 2, 3

6 weeks

3

3, 3, 3

3, 3, 3

8 weeks

5

3, 3, 3, 3, 3

3, 3, 3, 3, 3

10 weeks

5

3, 3, 3, 4, 4

3, 3, 3, 3, 3

12 weeks

5

4, 4, 4, 4, 5

3, 3, 3, 3, 3

14 weeks

5

4, 4, 4, 4, 4

4, 4, 4, 4, 4

16 weeks

5

4, 5, 5, 5, 5

3, 3, 4, 4, 4

18 weeks

5

4, 5, 5, 5, 5

3, 4, 4, 4, 4

20 weeks

4

5, 5, 5, 5

4, 4, 4, 4

22 weeks

4

5, 5, 5, 5

5, 5, 5, 5

24 weeks

4

5, 5, 5, 5

5, 5, 5, 5

26 weeks

4

5, 5, 5, 6

3, 5, 6, 6

28 weeks

3

5, 6, 6

5, 5, 6

30 weeks

3

4, 6, 6

4, 6, 6

32 weeks

3

5, 5, 5

5, 5, 5

36 weeks

3

5, 5, 5

5, 5, 5

40 weeks

4

5, 5, 5, 5

5, 5, 5, 5

  1. Tissue sections were evaluated for histopathological scores of 1 (no tumor), 2 (low grade PIN), 3 (high-grade PIN), 4 (well-differentiated tumor), 5 (moderately differentiated tumor), and 6 (poorly differentiated tumor) depending on the presence and progression of lesions. Individual grades are presented for each age group and lobe.