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Table 1 Histopathological analysis of the ventral and dorsolateral prostate lobes of SV-40 Tag rats fed control AIN-76A diet

From: Characterization of SV-40 Tag rats as a model to study prostate cancer

   Histopathological
Grades
Histopathological
Grades
Age n (Ventral Prostate) (Dorsolateral prostate)
1 day 2 1, 1 1, 1
1 week 4 1, 1, 1, 1 1, 1, 1, 1
2 weeks 6 2, 2, 2, 2, 2, 2 1, 1, 2, 2, 2, 2
3 weeks 2 2, 2 2, 2
4 weeks 2 3, 3 2, 2
5 weeks 4 2, 2, 3, 3 1, 2, 2, 3
6 weeks 3 3, 3, 3 3, 3, 3
8 weeks 5 3, 3, 3, 3, 3 3, 3, 3, 3, 3
10 weeks 5 3, 3, 3, 4, 4 3, 3, 3, 3, 3
12 weeks 5 4, 4, 4, 4, 5 3, 3, 3, 3, 3
14 weeks 5 4, 4, 4, 4, 4 4, 4, 4, 4, 4
16 weeks 5 4, 5, 5, 5, 5 3, 3, 4, 4, 4
18 weeks 5 4, 5, 5, 5, 5 3, 4, 4, 4, 4
20 weeks 4 5, 5, 5, 5 4, 4, 4, 4
22 weeks 4 5, 5, 5, 5 5, 5, 5, 5
24 weeks 4 5, 5, 5, 5 5, 5, 5, 5
26 weeks 4 5, 5, 5, 6 3, 5, 6, 6
28 weeks 3 5, 6, 6 5, 5, 6
30 weeks 3 4, 6, 6 4, 6, 6
32 weeks 3 5, 5, 5 5, 5, 5
36 weeks 3 5, 5, 5 5, 5, 5
40 weeks 4 5, 5, 5, 5 5, 5, 5, 5
  1. Tissue sections were evaluated for histopathological scores of 1 (no tumor), 2 (low grade PIN), 3 (high-grade PIN), 4 (well-differentiated tumor), 5 (moderately differentiated tumor), and 6 (poorly differentiated tumor) depending on the presence and progression of lesions. Individual grades are presented for each age group and lobe.