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Figure 1 | BMC Cancer

Figure 1

From: Expression of the glioma-associated oncogene homolog (GLI) 1in human breast cancer is associated with unfavourable overall survival

Figure 1

Elevated expression of GLI1 mRNA in breast cancer cell lines. Semiquantitative realtime PCR (Light Cycler) analysis for GLI1 expression was performed on reverse transcribed RNA extracted from non-malignant (grey bars) and malignant breast cell lines (black bars). Expression data were related to GLI1 mRNA expression in the human mammary epithelial cell line HMEC (set to 1). In five of eight analysed malignant mammary cell lines (SKBR3, MDA-MB468, BT20, MDA-MB231 and MDA-MB435s) increased levels of GLI1 mRNA expression were found. GLI1 mRNA expression in normal human epithelial mammary cell lines HMEC and MCF12A cells is relatively low, except for cell line MCF10A which also presents abundant GLI1 expression.

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