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Table 5 Multivariate analysis considering the influence of age (>70 vs. ≤70 years) and comorbidities (1. any comorbidity, 2. specific comorbidities) on individual symptoms

From: Impact of age and comorbidities on health-related quality of life for patients with prostate cancer: evaluation before a curative treatment

question

risk factor

hazard ratio

95% confidence interval

p-value

leaking urine ≥once a day

comorbidity

2.2

1.2-3.8

< 0.01

 

coronary heart disease

1.7

1.0-2.9

0.06

 

diabetes

1.9

1.0-3.7

0.06

no complete urinary control

age

1.9

1.3-2.7

< 0.01

great/moderate problem with frequent urination

comorbidity

2.0

1.2-3.3

< 0.01

 

diabetes

3.3

1.9-5.9

< 0.01

great/moderate problem with urinary function overall

comorbidity

2.2

1.2-3.9

< 0.01

 

diabetes

2.5

1.3-4.8

< 0.01

erections not firm enough for intercourse

age

2.8

1.7-4.7

< 0.01

 

comorbidity

1.7

1.0-2.9

0.04

 

diabetes

7.0

2.3-21

< 0.01

great/moderate problem with sexual function overall

age

1.8

1.1-3.7

0.04

 

comorbidity

1.9

1.1-3.5

0.03

 

diabetes

2.9

1.3-6.2

< 0.01

hot flashes ≥once a day

comorbidity

3.5

1.0-12

0.05

 

COPD

5.6

1.9-16

< 0.01

lack of energy ≥once a day

age

0.4

0.2-1.0

< 0.05

 

comorbidity

4.2

1.4-12

0.01

great/moderate problem with hot flashes

COPD

4.5

1.5-13

< 0.01

great/moderate problem with lack of energy

comorbidity

2.7

1.1-6.4

0.03

  1. COPD: chronic obstructive pulmonary disease