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Table 1 Comparison of Cyr61, CTGF and THBS1 immunohistochemisty wih clinicopathological features in patients with ESCC

From: Expression and prognostic significance of THBS1, Cyr61 and CTGF in esophageal squamous cell carcinoma

 

THBS1†

Cyr61†

CTGF†

 

n

-

+

P

n

-

+

P

n

-

+

P

Age(years)

            

≤ 57

43

6

37

0.494

43

21

22

0.987

43

25

18

0.184

>57

37

3

34

 

37

18

19

 

37

16

21

 

Gender

            

Male

58

6

52

0.700

58

29

29

0.805

58

33

25

0.101

Female

22

3

19

 

22

10

12

 

22

8

14

 

Regional lymph node

            

N0

48

2

46

0.026*

48

23

25

0.855

48

27

21

0.273

N1

32

7

25

 

32

16

16

 

32

14

18

 

Primary tumor

            

T1

4

1

3

 

4

2

2

 

4

3

1

 

T2

6

0

6

 

6

3

3

 

6

2

4

 

T3

64

7

57

0.479

64

30

34

0.868

64

34

30

0.501

T4

6

1

5

 

6

4

2

 

6

2

4

 

Histologic grade

            

Well differentiated

24

1

23

 

24

11

13

 

24

11

13

 

Moderately differentiated

48

6

42

0.179

48

22

26

0.355

48

26

22

0.844

Poorly differentiated

8

2

6

 

8

6

2

 

8

4

4

 

TNM Stage

            

I/IIa

45

1

44

 

45

21

24

 

45

26

19

 

IIb/III

35

8

27

0.009*

35

18

17

0.673

35

15

20

0.185

ESCC

80

8

72

 

80

39

41

 

80

41

39

 

Normal mucosa

38

31

7

0.000*

38

34

4

0.000*

38

30

8

0.004*

  1. TNM: tumor node metastasis; †: (-) = nonoverexpressor; (+) = overexpressor.
  2. *Significant at P < 0.05 level.
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