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Table 1 Comparison of Cyr61, CTGF and THBS1 immunohistochemisty wih clinicopathological features in patients with ESCC

From: Expression and prognostic significance of THBS1, Cyr61 and CTGF in esophageal squamous cell carcinoma

  THBS1 Cyr61 CTGF
  n - + P n - + P n - + P
Age(years)             
≤ 57 43 6 37 0.494 43 21 22 0.987 43 25 18 0.184
>57 37 3 34   37 18 19   37 16 21  
Gender             
Male 58 6 52 0.700 58 29 29 0.805 58 33 25 0.101
Female 22 3 19   22 10 12   22 8 14  
Regional lymph node             
N0 48 2 46 0.026* 48 23 25 0.855 48 27 21 0.273
N1 32 7 25   32 16 16   32 14 18  
Primary tumor             
T1 4 1 3   4 2 2   4 3 1  
T2 6 0 6   6 3 3   6 2 4  
T3 64 7 57 0.479 64 30 34 0.868 64 34 30 0.501
T4 6 1 5   6 4 2   6 2 4  
Histologic grade             
Well differentiated 24 1 23   24 11 13   24 11 13  
Moderately differentiated 48 6 42 0.179 48 22 26 0.355 48 26 22 0.844
Poorly differentiated 8 2 6   8 6 2   8 4 4  
TNM Stage             
I/IIa 45 1 44   45 21 24   45 26 19  
IIb/III 35 8 27 0.009* 35 18 17 0.673 35 15 20 0.185
ESCC 80 8 72   80 39 41   80 41 39  
Normal mucosa 38 31 7 0.000* 38 34 4 0.000* 38 30 8 0.004*
  1. TNM: tumor node metastasis; : (-) = nonoverexpressor; (+) = overexpressor.
  2. *Significant at P < 0.05 level.