Preoperative serum carcinoembryonic antigen, albumin and age are supplementary to UICC staging systems in predicting survival for colorectal cancer patients undergoing surgical treatment

Table 8 Univariate and multivariate analysis of prognostic indicators on cancer-specific survival for stage III colorectal cancer patients

Parameters	Number	Univariate analysis		Multivariate analysis
		Hazard ratio (95% CI) P value		Hazard ratio (95% CI) P value
Age (≥65/<65)years	189/193	1.33(0.90–1.96)	0.148	-	-
Sex (Male/Female)	198/184	0.74(0.52–1.05)	0.092	-	-
Site (Colon/Rectum)	263/119	0.96(0.66–1.40)	0.818	-	-
Tumor size (≥5/<5)cm	170/212	1.24(0.86–1.78)	0.252	-	-
BMI^a (≥24/≥18.5–24/<18.5)	123/150/109	1.01(0.63–1.61)	0.984	-	-
Albumin (<3.5/≥3.5)gm/dl	110/272	1.35(0.85–2.15)	0.207	-	-
Histology (PD/MD/WD^b)	62/278/42	2.11(0.91–4.92)	0.083	-	-
CEA^c (≥5/<5) ng/ml	193/189	1.74(1.22–2.50)	0.002	1.74(1.22–2.50)	0.002

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