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Table 7 Univariate and multivariate analysis of prognostic indicators on overall survival for stage II colorectal cancer patients

From: Preoperative serum carcinoembryonic antigen, albumin and age are supplementary to UICC staging systems in predicting survival for colorectal cancer patients undergoing surgical treatment

Parameters

Number

Univariate analysis

Multivariate analysis

  

Hazard ratio (95% CI) P value

Hazard ratio (95% CI) P value

Age (≥65/<65) years

290/205

1.97(1.33–2.91)

0.001

1.72(1.05–2.82)

0.003

Sex (Male/Female)

281/214

1.80(0.76–1.54)

0.670

-

-

Site (Colon/Rectum)

334/161

1.03(0.71–1.51)

0.864

-

-

Tumor size (≥5/<5) cm

253/242

1.04(0.72–1.49)

0.843

-

-

BMIa (≥24/<18.5–24/<18.5)

146/185/164

0.94(0.54–1.63)

0.969

-

-

Albumin (<3.5/≥3.5) gm/dl

169/326

1.79(1.17–2.75)

0.008

-

0.138

Histology (PD/MD/WDb)

48/367/80

2.42(0.97–6.03)

0.057

-

-

CEAc(≥5/<5) ng/ml

214/281

2.08(1.39–3.13)

<0.001

2.17(1.39–3.40)

0.001

  1. aBody mass index
  2. bPoorly differentiated; Moderately differentiated; Well differentiated
  3. cCarcinoembrynic antigen