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Table 7 Univariate and multivariate analysis of prognostic indicators on overall survival for stage II colorectal cancer patients

From: Preoperative serum carcinoembryonic antigen, albumin and age are supplementary to UICC staging systems in predicting survival for colorectal cancer patients undergoing surgical treatment

Parameters Number Univariate analysis Multivariate analysis
   Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
Age (≥65/<65) years 290/205 1.97(1.33–2.91) 0.001 1.72(1.05–2.82) 0.003
Sex (Male/Female) 281/214 1.80(0.76–1.54) 0.670 - -
Site (Colon/Rectum) 334/161 1.03(0.71–1.51) 0.864 - -
Tumor size (≥5/<5) cm 253/242 1.04(0.72–1.49) 0.843 - -
BMIa (≥24/<18.5–24/<18.5) 146/185/164 0.94(0.54–1.63) 0.969 - -
Albumin (<3.5/≥3.5) gm/dl 169/326 1.79(1.17–2.75) 0.008 - 0.138
Histology (PD/MD/WDb) 48/367/80 2.42(0.97–6.03) 0.057 - -
CEAc(≥5/<5) ng/ml 214/281 2.08(1.39–3.13) <0.001 2.17(1.39–3.40) 0.001
  1. aBody mass index
  2. bPoorly differentiated; Moderately differentiated; Well differentiated
  3. cCarcinoembrynic antigen