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Table 2 Univariate and multivariate analysis of prognostic indicators on cancer-specific survival for colorectal cancer patients

From: Preoperative serum carcinoembryonic antigen, albumin and age are supplementary to UICC staging systems in predicting survival for colorectal cancer patients undergoing surgical treatment

Parameters Number Univariate analysis Multivariate analysis
   Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
Age (≥65/<65)years 743/624 1.17(0.97–1.41) 0.930 - -
Sex (Male/Female) 757/610 1.24(1.03–1.50) 0.022 - 0.281
Site (Colon/Rectum) 920/447 1.19(0.98–1.46) 0.085 - -
Tumor size (≥5/<5)cm 539/774 1.28(1.05–1.56) 0.015 - 0.411
BMIa (≥24/≥18.5–24/<18.5) 434/516/417 0.84(0.64–1.09) 0.185 - -
Albumin (<3.5/≥3.5)gm/dl 392/975 1.72(1.38–2.14) <0.001 1.45(1.09–1.92) 0.011
Histology (PD/MD/WDb) 118/1066/183 3.05(1.95–4.77) <0.001 - 0.341
UICCc stage (III&IV/I&II) 630/737 3.96(3.22–4.87) <0.001 3.25(2.42–4.36) <0.001
CEAd (≥5/<5) ng/ml 643/724 2.91(2.34–3.62) <0.001 2.38(1.77–3.20) <0.001
  1. aBody mass index
  2. bPoorly differentiated; Moderately differentiated; Well differentiated
  3. cInternational Union Against Cancer
  4. dCarcinoembrynic antigen
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BMC Cancer

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