Preoperative serum carcinoembryonic antigen, albumin and age are supplementary to UICC staging systems in predicting survival for colorectal cancer patients undergoing surgical treatment

Table 2 Univariate and multivariate analysis of prognostic indicators on cancer-specific survival for colorectal cancer patients

Parameters	Number	Univariate analysis		Multivariate analysis
		Hazard ratio (95% CI) P value		Hazard ratio (95% CI) P value
Age (≥65/<65)years	743/624	1.17(0.97–1.41)	0.930	-	-
Sex (Male/Female)	757/610	1.24(1.03–1.50)	0.022	-	0.281
Site (Colon/Rectum)	920/447	1.19(0.98–1.46)	0.085	-	-
Tumor size (≥5/<5)cm	539/774	1.28(1.05–1.56)	0.015	-	0.411
BMI^a (≥24/≥18.5–24/<18.5)	434/516/417	0.84(0.64–1.09)	0.185	-	-
Albumin (<3.5/≥3.5)gm/dl	392/975	1.72(1.38–2.14)	<0.001	1.45(1.09–1.92)	0.011
Histology (PD/MD/WD^b)	118/1066/183	3.05(1.95–4.77)	<0.001	-	0.341
UICC^c stage (III&IV/I&II)	630/737	3.96(3.22–4.87)	<0.001	3.25(2.42–4.36)	<0.001
CEA^d (≥5/<5) ng/ml	643/724	2.91(2.34–3.62)	<0.001	2.38(1.77–3.20)	<0.001

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