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Table 2 HPV viral load and cervical cytology

From: Human papillomavirus prevalence, viral load and pre-cancerous lesions of the cervix in women initiating highly active antiretroviral therapy in South Africa: a cross-sectional study

Cervical cytology

N

Median HPV Viral load in RLUa

(interquartile range)

Normal

33

1.19 (0.19 – 14.30)

 

17

14.3 (3.28 – 190.06)

ASCUS

15

48.19 (0.59 – 218.51)

 

11

90.27 (33.59 – 232.08)

LSIL

39

308.33 (54.31 – 1259.64)

 

37

365.49 (82.06 – 1259.64)

HSIL

10

594.55 (177.5 – 1504.88)

 

10

594.55 (177.5 – 1504.88)

For HC2 all samples: Ptrend < 0.0001

  

For HC2 positives only: P trend = 0.002

  
  1. aViral load in regular types represents viral load from all samples with HC2 testing and in italics from the HC2 positive samples only
  2. HPV, human papillomavirus; HC2, Hybrid Capture 2; RLU, relative light units; ASCUS, atypical squamous cells of undetermined significance; LSIL, low grade squamous intra-epithelial lesions; HSIL, high-grade squamous intraepithelial lesions