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Table 1 Cox regression analysis for various potential prognostic factors in survival

From: Increased serum hepcidin-25 level and increased tumor expression of hepcidin mRNA are associated with metastasis of renal cell carcinoma

    Overall survival in 53 clear cell renal cell carcinomas
Variable Unfavorable/favorable characteristics No. of Patients Analysis Relative risk 95% confidential interval P value
    Univariate (U) 18.529 5.287 – 27.819 < 0.0001
Karnofsky PS < 80%/> 80% 5/48     
    Multivariate (M) 24.718 2.793 – 11.729 0.0029
    U 35.194 4.359 – 284.127 0.0008
Grade 4/3/2/1 0/15/30/8     
    M 85.943 4.123 – 1791.603 0.004
    U 10.667 1.349 – 84.339 0.0248
pT 4.3/2.1 15/38     
    M 6.512 0.448 – 94.642 0.17
    U 5.585 1.558 – 20.017 0.0083
Metastasis M1/M0 18/35     
    M 3.188 0.622 – 11.612 0.1273
    U 4.177 1.105 – 15.784 0.0351
Hepcidin mRNA high/low 25/28     
    M 5.824 0.846 – 40.092 0.0734