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Table 1 Cox regression analysis for various potential prognostic factors in survival

From: Increased serum hepcidin-25 level and increased tumor expression of hepcidin mRNA are associated with metastasis of renal cell carcinoma

   

Overall survival in 53 clear cell renal cell carcinomas

Variable

Unfavorable/favorable characteristics

No. of Patients

Analysis

Relative risk

95% confidential interval

P value

   

Univariate (U)

18.529

5.287 – 27.819

< 0.0001

Karnofsky PS

< 80%/> 80%

5/48

    
   

Multivariate (M)

24.718

2.793 – 11.729

0.0029

   

U

35.194

4.359 – 284.127

0.0008

Grade

4/3/2/1

0/15/30/8

    
   

M

85.943

4.123 – 1791.603

0.004

   

U

10.667

1.349 – 84.339

0.0248

pT

4.3/2.1

15/38

    
   

M

6.512

0.448 – 94.642

0.17

   

U

5.585

1.558 – 20.017

0.0083

Metastasis

M1/M0

18/35

    
   

M

3.188

0.622 – 11.612

0.1273

   

U

4.177

1.105 – 15.784

0.0351

Hepcidin mRNA

high/low

25/28

    
   

M

5.824

0.846 – 40.092

0.0734