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Table 1 Incidence of microscopic lesions and other microscopic abnormalities in NMU-treated whole mounted abdominal-inguinal mammary glands

From: Histological analysis of low dose NMU effects in the rat mammary gland

NMU dose (mg/kg BW)

12 weeks incidence (%) Ω

22 weeks incidence (%)Ω

25–30 weeks incidence (%) §

0

0/6 (0)

0/5 (0)

0/9 (0) ab

10

0/6 (0)

0/6 (0)

2/38 (5.3) a

20

0/6 (0)

1/6 (16.6)

9/37 (24.3) bc

30

2/5 (40.0)

3/5 (60.0)

9/27 (33.3) c

50

4/5 (80.0)

3/4 (75.0)

21/26 (80.8) d

  1. Ω indicates that the incidence was calculated 'per mammary gland' whereas § denotes the incidence calculated using abdominal-inguinal mammary glands from the left and right side of each animal. Different superscripts denote statistically significant differences (p < 0.05).