Skip to main content

Table 2 Overall objective response rate of patients at cycle 3 and maintained to cycle 5 or end of treatment.

From: Phase II assessment of talabostat and cisplatin in second-line stage IV melanoma

Timepoint

ITT Population

Evaluable Population

   Overall response to treatmenta

(N = 74)

(N = 40)

Cycle 3, Day 1

  

   CR

0

0

   PR

3 (4.1)b

3 (7.5)

   SD

34 (45.9)

25 (62.5)

Cycle 5, Day 1

  

   CR

0

0

   PR

3 (4.1)

3 (7.5)

   SD

16 (21.6)

13 (32.5)

End of treatment or early termination

  

   CR

0

0

   PR

2 (2.7)

1 (2.5)

   SD

10 (13.5)

7 (17.5)

  1. ITT = intention-to-treat; CR = complete response; PR = partial response; SD = stable disease; PD = progressive disease
  2. a Response is based on the investigator's assessment using RECIST.
  3. b N (%).