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Table 2 Hepatic antioxidase and lipid peroxidation

From: Assessment of the effect of betaine on p16 and c-mycDNA methylation and mRNA expression in a chemical induced rat liver cancer model

week

 

GSH

mgGSH/gprot

GST

U/mgprot

MDA

nmol/mgprot

SOD

U/mgprot

T-AOC

U/mgprot

8 w

control

35.77 ± 3.39

27.37 ± 2.63

0.166 ± 0.055

170.09 ± 33.93

0.269 ± 0.089

 

model

42.45 ± 6.87

38.62 ± 2.55*

0.357 ± 0.152*

164.98 ± 56.91

0.609 ± 0.248

 

1%betaine

39.05 ± 6.77

31.36 ± 3.10

0.145 ± 0.068▲

190.86 ± 55.32

0.516 ± 0.201

 

2%betaine

41.23 ± 2.59

35.14 ± 3.29*

0.361 ± 0.116*

178.75 ± 37.26

1.152 ± 0.407*▲

 

4%betaine

41.34 ± 5.21

35.23 ± 4.22*

0.334 ± 0.124*

183.74 ± 83.19

0.755 ± 0.361*▲

15 w

control

38.21 ± 6.47

27.79 ± 6.73

0.236 ± 0.088

167.70 ± 44.01

0.363 ± 0.096

 

model

38.22 ± 9.11

29.29 ± 4.23

0.299 ± 0.087

150.44 ± 57.59

0.912 ± 0.290

 

1%betaine

40.19 ± 4.96

26.41 ± 3.46

0.222 ± 0.032

161.79 ± 40.13

0.564 ± 0.184

 

2%betaine

39.99 ± 6.07

32.04 ± 6.89

0.231 ± 0.062

184.92 ± 38.38

0.942 ± 0.183

 

4%betaine

36.13 ± 4.29

25.99 ± 5.07

0.307 ± 0.076

152.49 ± 45.54

0.777 ± 0.184

  1. *Compared with the control group, p < 0.05; â–²Compared with the model group, p < 0.05.