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Table 11 Potential association of patient and tumor variables with a positive final margin status (i.e., as defined as either having a positive margin, a close margin, or a positive re-resection margin) as determined by univariate and multivariate analyses

From: Standardized and reproducible methodology for the comprehensive and systematic assessment of surgical resection margins during breast-conserving surgery for invasive breast cancer

Patient and tumor variables

Univariate P-value

Multivariate P-value

Age

0.601

NA

Height

0.469

NA

Weight

0.977

NA

Body mass index

0.799

NA

Race

0.792

NA

Menopausal status

0.777

NA

Breast sidedness

0.296

NA

Breast size

0.771

NA

Neoadjuvant therapy

0.655

NA

Originally palpable mass

0.647

NA

Tumor size

0.034

0.066

Tumor location

0.411

NA

Tumor histopathology (invasive lobular carcinoma)

0.095

0.052

Histologic grade

0.727

NA

Estrogen receptor positive

0.541

NA

Progesterone receptor positive

0.132

NA

Her 2 Neu positive

0.473

NA

Lymphovascular invasion

0.374

NA

Associated DCIS

0.032

0.015

Associated axillary lymph node involvement

0.182

NA

Type of original diagnostic breast biopsy

0.430

NA

  1. DCIS, ductal carcinoma in situ