Effect of ginsenoside Rg3 and gemcitabine on necrosis of tumor. Multi-local and larger areas of tumor necrosis (arrow) in the combination (Figure 2D) and ginsenoside Rg3 group (Figure 2C), and only smaller areas of tumor necrosis detected in the gemcitabine (Figure 2B) and control group (Figure 2A) detected by color Doppler ultrasound. E: necrosis rate of tumor (necrosis rate of tumor = tumor necrosis area/whole tumor area × 100%). Necrosis rate of tumor was assessed using pathological slices way. ▲P < 0.05 vs control group; ■P < 0.05 vs gemcitabine group.