Figure 1
Effect of ginsenoside Rg3 and gemcitabine on tumor growth and survival. A: tumor growth curve; B: inhibitive rate of tumor; C: survival curve. Tumor volume (TV) (mm3) = (width2 × length)/2. Inhibitive rate of tumor (%) = (1- average tumor weight in treated group/average tumor weight in control) × 100%. Survival curves were constructed according to the Kaplan-Meier method and statistical significance was determined by the log-rank test. 1: control group; 2: gemcitabine group; 3: ginsenoside Rg3 group; 4: combination group. ▲P < 0.05 vs control group; □P < 0.05 vs gemcitabine group; ■P < 0.05 vs ginsenoside Rg3 group. Combined therapy with ginsenoside Rg3 and gemcitabine enhanced efficacy on suppression of tumor growth and prolongation of the survival.