Figure 5From: Establishment and characterization of pleomorphic adenoma cell systems: an in-vitro demonstration of carcinomas arising secondarily from adenomas in the salivary gland Mutational analysis of the p53 gene in genomic DNA from pleomorphic adenoma cells in the primary culture as well as from the five SM-AP cell systems. PCR-amplicons for exons 5, 6 and 7 of the p53 gene were directly sequenced, and the deletion of the last base G of codon 249 (AGG to AG-) in exon 7 was shared by all of the cell systems and the primary culture.Back to article page