Skip to main content
Figure 4 | BMC Cancer

Figure 4

From: Establishment and characterization of pleomorphic adenoma cell systems: an in-vitro demonstration of carcinomas arising secondarily from adenomas in the salivary gland

Figure 4

Fluorescence in-situ hybridization (FISH) for screening of break points for the translocation, t(9;13)(p13;q12) in SM-AP5, by using BAC clones. Panel A, mapping of BAC clones of chromosome 9 (a) and FISH for 9p13.2 by BAC 1537E12 (b) and for 9p13.1 by BAC 1405F1 (c). Panel B, mapping of BAC clones of chromosome 13 (a) and FISH for 13q12.2 by BAC 1325C2 (b) and for 13q13.1 by BAC 1213F4 (c). × 800. Signals of BAC clones, 1537E12 and1405F1 for chromosome 9p13.2 (A-b) and 9p13.1(A-c), 1325C2 for chromosome 13q12.2 (B-c) were detected as clear single and/or paired fluorescence dots on the translocation t(9;13)(p13;q12) chromosome, while no signal for BAC clone 1213F4 for chromosome 13q13.1 was seen (B-b).

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us