Survival plots for AP4 in subtypes defined by proliferation markers. Here, the MKI67 +/- partition is used as a surrogate for the Ki-67 proliferation index. Combining this with tumor grade gives subtypes defined by clinical proliferation markers. The domain for this analysis is the same set of 738 samples used in the study of clinical subtypes. The subtypes are indicated above the panels. AP4 improves on the prognostic power of these subtypes, except on the small group of grade 3 tumors that are MKI67 -. AP4 is vacuous on MKI67 + since all such samples are AP4+.