TY - JOUR AU - Collins, V. P. PY - 2004 DA - 2004// TI - Brain tumours: classification and genes JO - J Neurol Neurosurg Psychiatry VL - 75 ID - Collins2004 ER - TY - JOUR AU - Stupp, R. AU - Hegi, M. E. AU - Bent, M. J. v. a. n. d. e. n. AU - Mason, W. P. AU - Weller, M. AU - Mirimanoff, R. O. AU - Cairncross, J. G. PY - 2006 DA - 2006// TI - Changing paradigms – an update on the multidisciplinary management of malignant glioma JO - Oncologist VL - 11 UR - https://doi.org/10.1634/theoncologist.11-2-165 DO - 10.1634/theoncologist.11-2-165 ID - Stupp2006 ER - TY - JOUR AU - Aschner, M. AU - Fitsanakis, V. A. AU - dos Santos, A. P. AU - Olivi, L. AU - Bressler, J. P. PY - 2006 DA - 2006// TI - Blood-brain barrier and cell-cell interactions: methods for establishing in vitro models of the blood-brain barrier and transport measurements JO - Methods Mol Biol VL - 341 ID - Aschner2006 ER - TY - JOUR AU - Eisenblatter, T. AU - Huwel, S. AU - Galla, H. J. PY - 2003 DA - 2003// TI - Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood-brain barrier JO - Brain Res VL - 971 UR - https://doi.org/10.1016/S0006-8993(03)02401-6 DO - 10.1016/S0006-8993(03)02401-6 ID - Eisenblatter2003 ER - TY - JOUR AU - Loscher, W. AU - Potschka, H. PY - 2005 DA - 2005// TI - Blood-brain barrier active efflux transporters: ATP-binding cassette gene family JO - NeuroRx VL - 2 UR - https://doi.org/10.1602/neurorx.2.1.86 DO - 10.1602/neurorx.2.1.86 ID - Loscher2005 ER - TY - JOUR AU - Begley, D. J. PY - 2004 DA - 2004// TI - ABC transporters and the blood-brain barrier JO - Curr Pharm Des VL - 10 UR - https://doi.org/10.2174/1381612043384844 DO - 10.2174/1381612043384844 ID - Begley2004 ER - TY - JOUR AU - Breedveld, P. AU - Pluim, D. AU - Cipriani, G. AU - Wielinga, P. AU - van Tellingen, O. AU - Schinkel, A. H. AU - Schellens, J. H. PY - 2005 DA - 2005// TI - The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients JO - Cancer Res VL - 65 UR - https://doi.org/10.1158/0008-5472.CAN-04-2416 DO - 10.1158/0008-5472.CAN-04-2416 ID - Breedveld2005 ER - TY - JOUR AU - Breedveld, P. AU - Beijnen, J. H. AU - Schellens, J. H. PY - 2006 DA - 2006// TI - Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs JO - Trends Pharmacol Sci VL - 27 UR - https://doi.org/10.1016/j.tips.2005.11.009 DO - 10.1016/j.tips.2005.11.009 ID - Breedveld2006 ER - TY - JOUR AU - Youdim, K. A. AU - Qaiser, M. Z. AU - Begley, D. J. AU - Rice-Evans, C. A. AU - Abbott, N. J. PY - 2004 DA - 2004// TI - Flavonoid permeability across an in situ model of the blood-brain barrier JO - Free Radic Biol Med VL - 36 UR - https://doi.org/10.1016/j.freeradbiomed.2003.11.023 DO - 10.1016/j.freeradbiomed.2003.11.023 ID - Youdim2004 ER - TY - JOUR AU - Hadjeri, M. AU - Barbier, M. AU - Ronot, X. AU - Mariotte, A. M. AU - Boumendjel, A. AU - Boutonnat, J. PY - 2003 DA - 2003// TI - Modulation of P-glycoprotein-mediated multidrug resistance by flavonoid derivatives and analogues JO - J Med Chem VL - 46 UR - https://doi.org/10.1021/jm021099i DO - 10.1021/jm021099i ID - Hadjeri2003 ER - TY - JOUR AU - Boumendjel, A. AU - Nicolle, E. AU - Moraux, T. AU - Gerby, B. AU - Blanc, M. AU - Ronot, X. AU - Boutonnat, J. PY - 2005 DA - 2005// TI - Piperazinobenzopyranones and phenalkylaminobenzopyranones: potent inhibitors of breast cancer resistance protein (ABCG2) JO - J Med Chem VL - 48 UR - https://doi.org/10.1021/jm050705h DO - 10.1021/jm050705h ID - Boumendjel2005 ER - TY - JOUR AU - Boumendjel, A. AU - Boccard, J. AU - Carrupt, P. A. AU - Nicolle, E. AU - Blanc, M. AU - Geze, A. AU - Choisnard, L. AU - Wouessidjewe, D. AU - Matera, E. L. AU - Dumontet, C. PY - 2008 DA - 2008// TI - Antimitotic and antiproliferative activities of chalcones: forward structure-activity relationship JO - J Med Chem VL - 51 UR - https://doi.org/10.1021/jm0708331 DO - 10.1021/jm0708331 ID - Boumendjel2008 ER - TY - JOUR AU - Andreu, J. M. AU - Gorbunoff, M. J. AU - Lee, J. C. AU - Timasheff, S. N. PY - 1984 DA - 1984// TI - Interaction of tubulin with bifunctional colchicine analogues: an equilibrium study JO - Biochemistry VL - 23 UR - https://doi.org/10.1021/bi00303a025 DO - 10.1021/bi00303a025 ID - Andreu1984 ER - TY - JOUR AU - Barbier, P. AU - Gregoire, C. AU - Devred, F. AU - Sarrazin, M. AU - Peyrot, V. PY - 2001 DA - 2001// TI - In vitro effect of cryptophycin 52 on microtubule assembly and tubulin: molecular modeling of the mechanism of action of a new antimitotic drug JO - Biochemistry VL - 40 UR - https://doi.org/10.1021/bi010926z DO - 10.1021/bi010926z ID - Barbier2001 ER - TY - JOUR AU - Weisenberg, R. C. AU - Borisy, G. G. AU - Taylor, E. W. PY - 1968 DA - 1968// TI - The colchicine-binding protein of mammalian brain and its relation to microtubules JO - Biochemistry VL - 7 UR - https://doi.org/10.1021/bi00852a043 DO - 10.1021/bi00852a043 ID - Weisenberg1968 ER - TY - JOUR AU - Lee, J. C. AU - Frigon, R. P. AU - Timasheff, S. N. PY - 1973 DA - 1973// TI - The chemical characterization of calf brain microtubule protein subunits JO - J Biol Chem VL - 248 ID - Lee1973 ER - TY - JOUR AU - Andreu, J. M. AU - Timasheff, S. N. PY - 1982 DA - 1982// TI - Conformational states of tubulin liganded to colchicine, tropolone methyl ether, and podophyllotoxin JO - Biochemistry VL - 21 UR - https://doi.org/10.1021/bi00268a023 DO - 10.1021/bi00268a023 ID - Andreu1982 ER - TY - JOUR AU - Schuck, P. AU - Rossmanith, P. PY - 2000 DA - 2000// TI - Determination of the sedimentation coefficient distribution by least-squares boundary modeling JO - Biopolymers VL - 54 UR - https://doi.org/3.0.CO;2-P DO - 3.0.CO;2-P ID - Schuck2000 ER - TY - JOUR AU - Romagnoli, R. AU - Baraldi, P. G. AU - Carrion, M. D. AU - Cara, C. L. AU - Cruz-Lopez, O. AU - Preti, D. AU - Tolomeo, M. AU - Grimaudo, S. AU - Di Cristina, A. AU - Zonta, N. PY - 2008 DA - 2008// TI - Design, synthesis, and biological evaluation of thiophene analogues of chalcones JO - Bioorg Med Chem VL - 16 UR - https://doi.org/10.1016/j.bmc.2008.04.026 DO - 10.1016/j.bmc.2008.04.026 ID - Romagnoli2008 ER - TY - JOUR AU - Liu, X. L. AU - Tee, H. W. AU - Go, M. L. PY - 2008 DA - 2008// TI - Functionalized chalcones as selective inhibitors of P-glycoprotein and breast cancer resistance protein JO - Bioorg Med Chem VL - 16 UR - https://doi.org/10.1016/j.bmc.2007.10.006 DO - 10.1016/j.bmc.2007.10.006 ID - Liu2008 ER - TY - JOUR AU - Chang, J. Y. AU - Chang, C. Y. AU - Kuo, C. C. AU - Chen, L. T. AU - Wein, Y. S. AU - Kuo, Y. H. PY - 2004 DA - 2004// TI - Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells JO - Mol Pharmacol VL - 65 UR - https://doi.org/10.1124/mol.65.1.77 DO - 10.1124/mol.65.1.77 ID - Chang2004 ER - TY - JOUR AU - Tait, S. W. AU - Green, D. R. PY - 2008 DA - 2008// TI - Caspase-independent cell death: leaving the set without the final cut JO - Oncogene VL - 27 UR - https://doi.org/10.1038/onc.2008.311 DO - 10.1038/onc.2008.311 ID - Tait2008 ER - TY - JOUR AU - Kitagawa, K. AU - Niikura, Y. PY - 2008 DA - 2008// TI - Caspase-independent mitotic death (CIMD) JO - Cell Cycle VL - 7 UR - https://doi.org/10.4161/cc.7.8.5720 DO - 10.4161/cc.7.8.5720 ID - Kitagawa2008 ER - TY - JOUR AU - Saif, M. W. AU - Tytler, E. AU - Lansigan, F. AU - Brown, D. M. AU - Husband, A. J. PY - 2009 DA - 2009// TI - Flavonoids, phenoxodiol, and a novel agent, triphendiol, for the treatment of pancreaticobiliary cancers JO - Expert Opin Investig Drugs VL - 18 UR - https://doi.org/10.1517/13543780902762835 DO - 10.1517/13543780902762835 ID - Saif2009 ER - TY - JOUR AU - Kasibhatla, S. AU - Baichwal, V. AU - Cai, S. X. AU - Roth, B. AU - Skvortsova, I. AU - Skvortsov, S. AU - Lukas, P. AU - English, N. M. AU - Sirisoma, N. AU - Drewe, J. PY - 2007 DA - 2007// TI - MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps JO - Cancer Res VL - 67 UR - https://doi.org/10.1158/0008-5472.CAN-07-0127 DO - 10.1158/0008-5472.CAN-07-0127 ID - Kasibhatla2007 ER - TY - JOUR AU - Peyrot, V. AU - Leynadier, D. AU - Sarrazin, M. AU - Briand, C. AU - Menendez, M. AU - Laynez, J. AU - Andreu, J. M. PY - 1992 DA - 1992// TI - Mechanism of binding of the new antimitotic drug MDL 27048 to the colchicine site of tubulin: equilibrium studies JO - Biochemistry VL - 31 UR - https://doi.org/10.1021/bi00160a024 DO - 10.1021/bi00160a024 ID - Peyrot1992 ER - TY - JOUR AU - Kim do, Y. AU - Kim, K. H. AU - Kim, N. D. AU - Lee, K. Y. AU - Han, C. K. AU - Yoon, J. H. AU - Moon, S. K. AU - Lee, S. S. AU - Seong, B. L. PY - 2006 DA - 2006// TI - Design and biological evaluation of novel tubulin inhibitors as antimitotic agents using a pharmacophore binding model with tubulin JO - J Med Chem VL - 49 UR - https://doi.org/10.1021/jm050761i DO - 10.1021/jm050761i ID - Kim do2006 ER - TY - JOUR AU - Lee, J. S. AU - Paull, K. AU - Alvarez, M. AU - Hose, C. AU - Monks, A. AU - Grever, M. AU - Fojo, A. T. AU - Bates, S. E. PY - 1994 DA - 1994// TI - Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen JO - Mol Pharmacol VL - 46 ID - Lee1994 ER - TY - JOUR AU - Seelig, A. AU - Landwojtowicz, E. PY - 2000 DA - 2000// TI - Structure-activity relationship of P-glycoprotein substrates and modifiers JO - Eur J Pharm Sci VL - 12 UR - https://doi.org/10.1016/S0928-0987(00)00177-9 DO - 10.1016/S0928-0987(00)00177-9 ID - Seelig2000 ER - TY - JOUR AU - Sawyer, A. J. AU - Piepmeier, J. M. AU - Saltzman, W. M. PY - 2006 DA - 2006// TI - New methods for direct delivery of chemotherapy for treating brain tumors JO - Yale J Biol Med VL - 79 ID - Sawyer2006 ER - TY - JOUR AU - Borlongan, C. V. AU - Emerich, D. F. PY - 2003 DA - 2003// TI - Facilitation of drug entry into the CNS via transient permeation of blood brain barrier: laboratory and preliminary clinical evidence from bradykinin receptor agonist, Cereport JO - Brain Res Bull VL - 60 UR - https://doi.org/10.1016/S0361-9230(03)00043-1 DO - 10.1016/S0361-9230(03)00043-1 ID - Borlongan2003 ER - TY - JOUR AU - Omuro, A. M. AU - Faivre, S. AU - Raymond, E. PY - 2007 DA - 2007// TI - Lessons learned in the development of targeted therapy for malignant gliomas JO - Mol Cancer Ther VL - 6 UR - https://doi.org/10.1158/1535-7163.MCT-07-0047 DO - 10.1158/1535-7163.MCT-07-0047 ID - Omuro2007 ER - TY - STD TI - The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2407/9/242/prepub UR - http://www.biomedcentral.com/1471-2407/9/242/prepub ID - ref33 ER -