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Figure 1 | BMC Cancer

Figure 1

From: Qualitative analysis of Adenomatous Polyposis Coli promoter: Hypermethylation, engagement and effects on survival of patients with esophageal cancer in a high risk region of the world, a potential molecular marker

Figure 1

The profile of APC promoter and the amplified products. The products of primary amplification with primers designed for promoter sequence without CpG dinucleotides were either 402 or 320 bp. The product of the first step of PCR was used for the second step amplification by applying primers, which specifically distinguish methylated from unmethylated cytosines. The products of the second amplification were 98 bp for methylated and 111 bp for unmethylated cytosine in CpG islands of promoter.

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BMC Cancer

ISSN: 1471-2407

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