|  |  |  | OR (95% CI)a |  | ||
---|---|---|---|---|---|---|---|
Gene | Genotype | Case | Control | Co-dominant | Dominant | Additive | raw p valueb |
TNF β 252 A/G (rs909253) | AA | 23 (29) | 83 (26) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |  |
 | AG | 43 (54) | 170 (54) | 0.9 (0.5–1.6) | 0.9 (0.5–1.5) | 0.9 (0.6–1.3) | 0.5110 |
 | GG | 13 (17) | 61 (20) | 0.8 (0.4–1.7) |  | 0.8 (0.4–1.7) |  |
TNF α-1031 T/C (rs1799964) | TT | 55 (66) | 205 (63) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |  |
 | TC | 25 (30) | 109 (34) | 0.8 (0.5–1.4) | 0.8 (0.5–1.4) | 0.9 (0.6–1.4) | 0.5915 |
 | CC | 3 (4) | 10 (3) | 1.1 (0.3–4.3) |  | 0.9 (0.3–1.9) |  |
TNF α-863 C/A (rs1800630) | CC | 64 (77) | 227 (70) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |  |
 | CA | 16 (19) | 90 (28) | 0.6 (0.3–1.1) | 0.7 (0.4–1.2) | 0.8 (0.5–1.3) | 0.3416 |
 | AA | 3 (4) | 6 (2) | 1.6 (0.4–6.9) |  | 0.6 (0.2–1.7) |  |
TNF α-857 C/T (rs1799724) | CC | 49 (58) | 227 (70) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |  |
 | CT | 33 (39) | 92 (28) | 1.7 (1.0–2.8)* | 1.7 (1.0–2.8)* | 1.6 (1.0–2.5)* | 0.0466 |
 | TT | 2 (3) | 6 (2) | 1.7 (0.3–9.2) |  | 2.6 (1.0–6.4)* |  |
TNF α-308 G/A (rs1800629) c | GG | 75 (90) | 288 (89) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |  |
 | GA | 8 (10) | 34 (11) | 0.8 (0.4–1.9) | 0.8 (0.3–1.7) | 0.7 (0.3–1.6) | 0.4439 |
 | AA | - | - | - |  | 0.5 (0.1–2.5) |  |
TNF a-238 G/A (rs361525) c | GG | 73 (88) | 305 (92) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | Â |
 | GA | 10 (12) | 26 (8) | 1.6 (0.7–3.6) | 1.6 (0.7–3.6) | 1.6 (0.7–3.6) | 0.2333 |
 | AA | - | - | - |  | 2.5 (0.5–12.1) |  |