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Table 2 Molecular and phenotypic characterizations of 40 breast cancer cell lines

From: Low-risk susceptibility alleles in 40 human breast cancer cell lines

Breast cancer cell lines

Breast cancer subtype

Intrinsic subtype

Protein expression

   

ER

PgR

ERBB2

3-neg

SUM185PE

Luminal-type

Luminal

-

-

-

+

BT483

Luminal-type

Luminal

+

-

+

-

MDA-MB-134VI

Luminal-type

Luminal

+

-

-

-

MDA-MB-175VII

Luminal-type

Luminal

+

-

-

-

MDA-MB-415

Luminal-type

Luminal

+

-

-

-

MPE600

Luminal-type

Luminal

+

-

+

-

SUM52PE

Lumina-type

Luminal

+

-

+

-

CAMA-1

Lumina-type

Luminal

+

+

+

-

MCF-7

Luminal-type

Luminal

+

+

-

-

ZR75-1

Luminal-type

Luminal

+

+

+

-

SUM44PE

Luminal-type

Luminal

+

+

-

-

T47D

Luminal-type

Luminal

+

+

-

-

MDA-MB-361

Luminal-type

Luminal

+

+

++

-

BT474

Luminal-type

Luminal

-

+

++

-

UACC812

Luminal-type

Luminal

-

+

++

-

ZR75-30

Luminal-type

Luminal

+

-

++

-

OCUB-F

Luminal-type

Luminal

-

-

++

-

SK-BR-5

Luminal-type

Luminal

-

-

++

-

SUM190PT

Luminal-type

nd

-

-

++

-

SUM225CWN

Luminal-type

nd

-

-

++

-

MDA-MB-330

Luminal-type

ERBB2

+

-

++

-

MDA-MB-453

Luminal-type

ERBB2

-

-

++

-

SK-BR-3

Luminal-type

ERBB2

-

-

++

-

EVSA-T

Luminal-type

ERBB2

-

-

++

-

UACC893

Luminal-type

ERBB2

-

-

++

-

BT20

Basal-type

Basal-like

-

-

-

+

HCC1937

Basal-type

Basal-like

-

-

-

+

MDA-MB-468

Basal-type

Basal-like

-

-

-

+

SUM149PT

Basal-type

Basal-like

-

-

-

+

SUM229PE

Basal-type

Basal-like

-

-

-

+

BT549

Basal-type

Normal-like

-

-

-

+

Hs578T

Basal-type

Normal-like

-

-

-

+

MDA-MB-157

Basal-type

Normal-like

-

-

-

+

MDA-MB-231

Basal-type

Normal-like

-

-

-

+

MDA-MB-436

Basal-type

Normal-like

-

-

-

+

SK-BR-7

Basal-type

Normal-like

-

-

-

+

SUM159PT

Basal-type

Normal-like

-

-

-

+

SUM1315MO2

Basal-type

Normal-like

-

-

-

+

SUM102PT

Basal-type

Normal-like

nd

nd

nd

nd

MDA-MB-435s

Basal-type

Normal-like

-

-

-

+

Total phenotype positives

  

14

8

13

16

  1. Phenotypic characterizations have been reported elsewhere and involved protein expression patterns of the cell lines for the breast cancer subtyping (cytokeratins, ER, PgR and ERBB2) and expression of the intrinsic gene set for the intrinsic subtyping (Hollestelle et al. submitted for publication). Protein expression: +, expressed; ++, over expressed; and -, not detectable; 3-neg, triple-negative.