Skip to main content

Advertisement

Table 2 Molecular and phenotypic characterizations of 40 breast cancer cell lines

From: Low-risk susceptibility alleles in 40 human breast cancer cell lines

Breast cancer cell lines Breast cancer subtype Intrinsic subtype Protein expression
    ER PgR ERBB2 3-neg
SUM185PE Luminal-type Luminal - - - +
BT483 Luminal-type Luminal + - + -
MDA-MB-134VI Luminal-type Luminal + - - -
MDA-MB-175VII Luminal-type Luminal + - - -
MDA-MB-415 Luminal-type Luminal + - - -
MPE600 Luminal-type Luminal + - + -
SUM52PE Lumina-type Luminal + - + -
CAMA-1 Lumina-type Luminal + + + -
MCF-7 Luminal-type Luminal + + - -
ZR75-1 Luminal-type Luminal + + + -
SUM44PE Luminal-type Luminal + + - -
T47D Luminal-type Luminal + + - -
MDA-MB-361 Luminal-type Luminal + + ++ -
BT474 Luminal-type Luminal - + ++ -
UACC812 Luminal-type Luminal - + ++ -
ZR75-30 Luminal-type Luminal + - ++ -
OCUB-F Luminal-type Luminal - - ++ -
SK-BR-5 Luminal-type Luminal - - ++ -
SUM190PT Luminal-type nd - - ++ -
SUM225CWN Luminal-type nd - - ++ -
MDA-MB-330 Luminal-type ERBB2 + - ++ -
MDA-MB-453 Luminal-type ERBB2 - - ++ -
SK-BR-3 Luminal-type ERBB2 - - ++ -
EVSA-T Luminal-type ERBB2 - - ++ -
UACC893 Luminal-type ERBB2 - - ++ -
BT20 Basal-type Basal-like - - - +
HCC1937 Basal-type Basal-like - - - +
MDA-MB-468 Basal-type Basal-like - - - +
SUM149PT Basal-type Basal-like - - - +
SUM229PE Basal-type Basal-like - - - +
BT549 Basal-type Normal-like - - - +
Hs578T Basal-type Normal-like - - - +
MDA-MB-157 Basal-type Normal-like - - - +
MDA-MB-231 Basal-type Normal-like - - - +
MDA-MB-436 Basal-type Normal-like - - - +
SK-BR-7 Basal-type Normal-like - - - +
SUM159PT Basal-type Normal-like - - - +
SUM1315MO2 Basal-type Normal-like - - - +
SUM102PT Basal-type Normal-like nd nd nd nd
MDA-MB-435s Basal-type Normal-like - - - +
Total phenotype positives    14 8 13 16
  1. Phenotypic characterizations have been reported elsewhere and involved protein expression patterns of the cell lines for the breast cancer subtyping (cytokeratins, ER, PgR and ERBB2) and expression of the intrinsic gene set for the intrinsic subtyping (Hollestelle et al. submitted for publication). Protein expression: +, expressed; ++, over expressed; and -, not detectable; 3-neg, triple-negative.