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Table 3 Effect of AhR and β-Catennin siRNA on proliferation in MCF10AT1 cell sub-lines selected over 20 passages in 17-β-Estradiol (p20 E2) or the ethanol vehicle (p20 C).

From: Characterization of MCF mammary epithelial cells overexpressing the Arylhydrocarbon receptor (AhR)

Cell lines:

P20C

P20E

Control neg-siRNA

100 ± 6.3

195 ± 10.1* a

β-Catenin siRNA

60 ± 4.2a

103 ± 12.5* a

AhR siRNA

63 ± 4.2a

86 ± 8.7* a

  1. Cells were measured 72 hours after plating. * p < 0.05 HRG vs. control, (a)p < 0.05 control vs. siRNA