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Table 1 Relationship between s-MKRN1-Abs and the clinicopathological variables in 73 patients with esophageal SCC

From: Identification of Makorin 1 as a novel SEREX antigen of esophageal squamous cell carcinoma

   s-MKRN1-Abs  
   Positive Negative  
   (18 patients) (55 patients)  
Characteristics   n (%) n (%) P value
Age     
   Median 65 yrs    
   Range 39–86 yrs    
  Under 59 yrs 6 (33) 21 (38)  
  Over 60 yrs 12 (67) 34 (62) 0.711
Sex Male 16 (89) 50 (91)  
  Female 2 (11) 5 (9) 0.555
Location Ce 0 (0) 4 (7)  
  Ut 4 (22) 7 (13)  
  Mt 9 (50) 29 (53)  
  Lt 4 (22) 9 (16)  
  Ae 1 (6) 4 (7)  
  Unknown 0 (0) 2 (4) 0.682
Tumor size     
   Median 58.6 mm    
   Range 15–140 mm    
  Under 29 mm 2 (11) 8 (15)  
  Over 30 mm 13 (72) 47 (85)  
  Unknown 3 (17) 0 (0) 0.636
Histopathological Grading GX 8 (44) 20 (37)  
  G1 6 (33) 5 (9)  
  G2 4 (22) 21 (38)  
  G3 0 (0) 9 (16) 0.008
Primary Tumor Tis 0 (0) 1 (2)  
  T1 3 (17) 16 (29)  
  T2 4 (22) 10 (18)  
  T3 5 (28) 13 (24)  
  T4 6 (33) 15 (27) 0.824
Regional Lymph Nodes N0 3 (17) 17 (31)  
  N1 15 (83) 38 (69) 0.194
Distant Metastasis M0 16 (89) 46 (84)  
  M1 2 (11) 9 (16) 0.455
Stage Grouping Stage 0 0 (0) 1 (2)  
  Stage I 1 (6) 12 (22)  
  Stage IIA 1 (6) 3 (5)  
  Stage IIB 6 (33) 11 (20)  
  Stage III 8 (44) 19 (35)  
  Stage IV 2 (11) 9 (16) 0.552
Tumor Markers     
   SCC-Ag Positive 7 (39) 19 (35)  
  Negative 11 (61) 32 (58)  
  ND 0 (0) 4 (7) 0.902
   CYFRA21-1 Positive 3 (17) 13 (24)  
  Negative 15 (83) 38 (69)  
  ND 0 (0) 4 (7) 0.340
   CEA Positive 2 (11) 12 (22)  
  Negative 16 (89) 37 (67)  
  ND 0 (0) 6 (11) 0.199
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