Figure 1

Foxp3 and IDO expression in the sentinel lymph nodes (SLN). This figure illustrates the expression of IDO (top row) and Foxp3 (bottom row) in a SLN with a 7 mm breast cancer metastasis at 100× (first column), and 400× (second column) magnification. Foxp3+ cells are located primarily in the paracortical regions, whereas IDO+ cells infiltrate perisinusoidal areas. The pericapsular fat is marked by the circle, the paracortex by the diamond, the marginal sinus by the arrowhead, and the medullary sinus by the diamond.