Table 2 Summary of analyses of RCC10 and 786-O cell lines.
Cell Line | Subtype | Epithelial Morphologya | VHL Instability | Aberrant ZO-1 | |
|---|---|---|---|---|---|
| Â | Â | RCC10 | 786-O | Â | Â |
Wild-type | - | + | + | - | - |
control | 1 | - | - | Â | +++ |
del 114–178 | 1 | - | - | +b | ++ |
RC161/2QW | 1 | - | - | +b | +++ |
S65W | 1 | - | N/D | + | ++ |
N78S | 1 | - | N/D | + | ++ |
L158P | 1 | - | N/D | + | +++ |
L188Q | 1 | +/- | + | + | +++ |
Y98H | 2A | + | + | - | - |
Y112H | 2A | + | + | - | N/D |
Y98N | 2B | + | + | +/- | + |
Y112N | 2B | + | + | - | N/D |
R167Q | 2B | + | +/- | + | ++ |
R167W | 2B | + | + | +b | N/D |
V84L | 2C | + | + | N/D | N/D |
L188V | 2C | + | + | - | - |