Hazard ratio point estimates tend to be larger in the TRANSBIG data set for ER positive tumors. The graphs were based on unsupervised hierarchical clustering analyses using the 5,000 randomly-generated unigene gene. Bars represent the median hazard ratio (HR) from univariate Cox regression analyses and the whiskers represent the inter-decile range (10%–90%) of the values. A. Results from analyses based on all tumors in each data set. B. Results from analyses based on ER positive tumors.