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Table 1 Patient Characteristics

From: CXCR4 expression on circulating pan-cytokeratin positive cells is associated with survival in patients with advanced non-small cell lung cancer

 

All patients

(N = 16)

Low risk group

(CXCR4 ≤ 2500 cells/ml)

(n = 11)

High risk group

(CXCR4 > 2500 cells/ml)

(n = 5)

Gender

   

   F

8

5

3

   M

8

6

2

Age

   

   Mean ± SD

69 ± 10

67 ± 11

74 ± 6

   Min-max, median

42–83, 73

42–79, 70

67–83, 73

Stage

   

   IA

2

2

0

   IIIA

1

0

1

   IIIB

1

1

0

   IV

12

8

4

ECOG PS

   

   0

10

7

3

   1

6

4

2

Histology

   

   Adenocarcinoma

6

4

2

   Large cell

1

0

1

   Squamous cell

2

1

1

   Not Specified

7

6

1

Tobacco (pack-years)

   

   0

2

2

0

   1–20

4

3

1

   >20

10

6

4

# of prior treatments

   

   0

14

9

5

   1

2

2

0

Mean Survival (weeks)

65 ± 50

79 ± 46

34 ± 50

Median Survival (weeks)

60 (6-NA)

NA (15-NA)

14 (6-NA)*

  1. NA, not achieved
  2. *p = 0.03 and hazard ratio of 0.23 (95% CI, 0.02–0.79) for median survival of low risk group versus high risk group (log-rank test).
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BMC Cancer

ISSN: 1471-2407

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