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Figure 5 | BMC Cancer

Figure 5

From: Identification of proteins involved in neural progenitor cell targeting of gliomas

Figure 5

A decrease in tumor proliferation after the addition of antibodies against the genes Gas6, AXL, CXCL1, CD81 and TPT1 was observed. Co-cultures of tumor N29 (A) and N32 (B) together with irradiated NPC (HiB5/ST14A), were treated by adding antibodies against Gas6, AXL, TPT1, CXCL1 and CD81. Cells were seeded together and allowed to attach before addition of the antibodies. The plates were pulsed with 3H-thymidine after 3 days in culture and cell division was measured as the amount of incorporated 3H-thymidine. The result is expressed as fold change, where 1 represents the inhibition by NPC alone on the tumor (dashed line). Values below 1 show a further decrease in tumor proliferation due to the addition of antibodies. White bars show HiB5 and black bars show ST14A cultures. Mean ± stdev: Statistical analysis was made using t-test and Mann Whitney Wilcoxon rank sum test * P < 0.05

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