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Table 1 Patient characteristics

From: Liposarcoma: exploration of clinical prognostic factors for risk based stratification of therapy

Variables No. of patients
  Total (n = 94) (%) Low (n = 72) High (n = 22)
Age, Median (range) 56 (20–80) 55 (20–80) 58.5 (24–75)
Gender    
   Male 53 (56.4%) 42 (58.3%) 11(50.0%)
   Female 41 (43.6%) 30 (41.7%) 11(50.0%)
Presentation status    
   Biopsy 49 (52.1%) 38 (52.8%) 11(50.0%)
   No prior biopsy or treatment 20 (21.3%) 17 (23.6%) 3(13.6%)
   Prior excision 25 (26.6%) 17 (23.6%) 8(36.4%)
Histologic variant    
   Well differentiated 50 (53.2%) - -
   Myxoid 22 (23.4%) - -
   Dedifferentiated 15 (16.0%) - -
   Round 5 (5.3%) - -
   Pleomorphic 2 (2.1%) - -
Primary site    
   Retroperitoneum 44 (46.8%) 31(43.0%) 13 (59.1%)
Without contiguous organ resection 32 (34.0%) 23 (31.9%) 9 (40.9%)
With contiguous organ resection 12 (12.8%) 8 (11.1%) 4 (18.2%)
   Lower extremity 24 (25.5%) 23 (31.9%) 1(4.5%)
   Upper extremity 9 (9.6%) 9 (12.5%) 0 (0)
   Trunk 17 (18.1%) 9 (12.5%) 8 (36.4%)
Tumor burden    
   Median (cm, range) 14 (2–48) 13 (2–45) 15 (2–48)
Margins    
   Negative margins 50 (53.2%) 42 (58.3%) 8 (36.4%)
   Positive micro margins 32 (34.0%) 24 (33.3%) 8 (36.4%)
   Positive gross margins 12 (12.8%) 6 (8.3%) 6 (27.3%)
Postoperative radiotherapy for primary disease    
   Median dose (cGy) 5300
(2500–6000)
5400
(2500–6000)
5000
(2600–6000)
   Yes 31 (33.0%) 22 (30.5%) 9 (40.9%)
Negative/microscopic/gross positive
(%)
17/10/4
(54.8/32.3/12.9)
13/8/1
(59.1/36.4/4.5)
4/2/3
(44.4/22.2/33.3)
   No 63 (67.0%) 50 (69.4%) 13 (59.1%)