Table 1 Patient characteristics
From: Liposarcoma: exploration of clinical prognostic factors for risk based stratification of therapy
Variables | No. of patients | ||
|---|---|---|---|
Total (n = 94) (%) | Low (n = 72) | High (n = 22) | |
Age, Median (range) | 56 (20–80) | 55 (20–80) | 58.5 (24–75) |
Gender | |||
Male | 53 (56.4%) | 42 (58.3%) | 11(50.0%) |
Female | 41 (43.6%) | 30 (41.7%) | 11(50.0%) |
Presentation status | |||
Biopsy | 49 (52.1%) | 38 (52.8%) | 11(50.0%) |
No prior biopsy or treatment | 20 (21.3%) | 17 (23.6%) | 3(13.6%) |
Prior excision | 25 (26.6%) | 17 (23.6%) | 8(36.4%) |
Histologic variant | |||
Well differentiated | 50 (53.2%) | - | - |
Myxoid | 22 (23.4%) | - | - |
Dedifferentiated | 15 (16.0%) | - | - |
Round | 5 (5.3%) | - | - |
Pleomorphic | 2 (2.1%) | - | - |
Primary site | |||
Retroperitoneum | 44 (46.8%) | 31(43.0%) | 13 (59.1%) |
Without contiguous organ resection | 32 (34.0%) | 23 (31.9%) | 9 (40.9%) |
With contiguous organ resection | 12 (12.8%) | 8 (11.1%) | 4 (18.2%) |
Lower extremity | 24 (25.5%) | 23 (31.9%) | 1(4.5%) |
Upper extremity | 9 (9.6%) | 9 (12.5%) | 0 (0) |
Trunk | 17 (18.1%) | 9 (12.5%) | 8 (36.4%) |
Tumor burden | |||
Median (cm, range) | 14 (2–48) | 13 (2–45) | 15 (2–48) |
Margins | |||
Negative margins | 50 (53.2%) | 42 (58.3%) | 8 (36.4%) |
Positive micro margins | 32 (34.0%) | 24 (33.3%) | 8 (36.4%) |
Positive gross margins | 12 (12.8%) | 6 (8.3%) | 6 (27.3%) |
Postoperative radiotherapy for primary disease | |||
Median dose (cGy) | 5300 (2500–6000) | 5400 (2500–6000) | 5000 (2600–6000) |
Yes | 31 (33.0%) | 22 (30.5%) | 9 (40.9%) |
Negative/microscopic/gross positive (%) | 17/10/4 (54.8/32.3/12.9) | 13/8/1 (59.1/36.4/4.5) | 4/2/3 (44.4/22.2/33.3) |
No | 63 (67.0%) | 50 (69.4%) | 13 (59.1%) |