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Figure 4 | BMC Cancer

Figure 4

From: P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients

Figure 4

The sensitivity of K562 and K562/BCRP cells to DM4 with or without BCRP inhibitor. K562 and K562/BCRP cells were treated with DM4 at different concentrations (3.125, 6.25, 12.5, 25, 50, 100 and 200 nM) in the presence or absence of FTC (1 μM) for 72 h, and then their sensitivity was measured by an MTT assay. All experiments were done in triplicate.

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