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Table 1 Summary of animal tumor data

From: The Ets dominant repressor En/Erm enhances intestinal epithelial tumorigenesis in ApcMin mice

  ApcMin
(n = 12)
ApcMin; Villin-En/Erm
(n = 11)
 
  Mean (SEM) Mean (SEM) p-value**
Animal age (months) 14.3 (1.3) 13.0 (1.1) 0.45
Tumor number (total) 6.8 (2.0) 16.5 (3.4) 0.03
   PSI 1.3 (0.1) 3.4 (0.2) 0.07
   MSI 2.8 (0.3) 8.4 (0.4) 0.03
   DSI 2.9 (0.3) 4.8 (0.4) 0.37
Tumor size (total; cm)* 0.31 (0.03) 0.31 (0.02) 0.89
   PSI 0.33 (0.07) 0.25 (0.04) 0.33
   MSI 0.20 (0.02) 0.27 (0.01) 0.001
   DSI 0.32 (0.04) 0.32 (0.02) 0.82
% tumors with stromal invasion 10.9 (4.6) 19.3 (4.6) 0.17
% histologically aggressive tumors 3.7 (2.8) 4.7 (2.4) 0.78
  1. * largest dimension from slide
  2. ** from two-tailed student t-test with unequal variance
  3. SEM: standard error of the mean
  4. PSI, MSI and DSI: proximal, mid and distal small intestine, respectively