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Table 1 Summary of animal tumor data

From: The Ets dominant repressor En/Erm enhances intestinal epithelial tumorigenesis in ApcMin mice

 

ApcMin

(n = 12)

ApcMin; Villin-En/Erm

(n = 11)

 
 

Mean (SEM)

Mean (SEM)

p-value**

Animal age (months)

14.3 (1.3)

13.0 (1.1)

0.45

Tumor number (total)

6.8 (2.0)

16.5 (3.4)

0.03

   PSI

1.3 (0.1)

3.4 (0.2)

0.07

   MSI

2.8 (0.3)

8.4 (0.4)

0.03

   DSI

2.9 (0.3)

4.8 (0.4)

0.37

Tumor size (total; cm)*

0.31 (0.03)

0.31 (0.02)

0.89

   PSI

0.33 (0.07)

0.25 (0.04)

0.33

   MSI

0.20 (0.02)

0.27 (0.01)

0.001

   DSI

0.32 (0.04)

0.32 (0.02)

0.82

% tumors with stromal invasion

10.9 (4.6)

19.3 (4.6)

0.17

% histologically aggressive tumors

3.7 (2.8)

4.7 (2.4)

0.78

  1. * largest dimension from slide
  2. ** from two-tailed student t-test with unequal variance
  3. SEM: standard error of the mean
  4. PSI, MSI and DSI: proximal, mid and distal small intestine, respectively