Figure 1
From: The Ets dominant repressor En/Erm enhances intestinal epithelial tumorigenesis in ApcMin mice
Intestinal histology and En/Erm expression in transgenic animals in the tumor study. (A) Representative histology (H+E-stained sections) of mid small intestine from non-transgenic (Tg-) and Villin-En/Erm transgenic (Tg+) animals under conditions of normal homeostasis. The transgenic animals show crypt-villus morphology indistinguishable from control non-transgenic animals. (B) Levels of Actin and En/Erm transgene RNA in non-transgenic (Tg-), and transgenic (Tg+) animals, as determined by RT-PCR (cycle number: 25).