Figure 3From: Low NKp30, NKp46 and NKG2D expression and reduced cytotoxic activity on NK cells in cervical cancer and precursor lesions NK cell specific lysis is decreased according to the natural history of cervical cancer: healthy women (6 controls) > LGSIL (6 cases) > HGSIL (5 cases) > cervical cancer (5 cases). NK cell cytotoxicity against K562 cells was evaluated in a 4 hour CFSE/7-AAD flow cytometry assay against K562 tumor line. Significant difference at 10:1 and 30:1 E:T ratios: Invasive Ca and HGSIL versus healthy women p < 0.0001 and p < 0.002, respectively.Back to article page