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Table 2 Semi-quantitative IHC results: ER, PR, COX-2 and Aromatase

From: In situaromatase expression in primary tumor is associated with estrogen receptor expression but is not predictive of response to endocrine therapy in advanced breast cancer

  

Let n = 46

Tam n = 39

Total (n = 85)

ER level (Allred score)

negative

≤ 2

3

2

5

Low

3

0

0

0

 

4

1

1

2

 

5

2

1

3

 

6

6

3

9

High

7

10

8

18

 

8

21

19

40

N.A. (not assessable)

3

5

8

Total positive

40

32

72

PR level (Allred score)

negative

≤ 2

9

9

18

Low

3

3

1

4

 

4

5

3

8

 

5

4

5

9

 

6

1

6

7

High

7

6

0

6

 

8

14

12

26

N.A. (not assessable)

4

3

7

Total positive

 

33

27

60

COX-2 level (Allred score)

negative

≤ 2

13

11

24

Low

3

0

2

2

 

4

5

4

9

 

5

10

2

12

 

6

7

6

13

High

7

5

7

12

 

8

1

0

1

N.A. (not assessable)

5

7

12

Total positive

 

28

21

49

Aromatase level (Carcinoma cell SIP score)

negative

0

10

5

15

Low

1

3

3

6

 

2

9

3

12

 

3

2

3

5

 

4

5

9

14

 

6

8

5

13

 

8

0

2

2

High

9

2

3

5

 

12

2

1

3

N.A. (not assessable)

5

5

10

Total positive

30

30

60