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Table 2 Semi-quantitative IHC results: ER, PR, COX-2 and Aromatase

From: In situaromatase expression in primary tumor is associated with estrogen receptor expression but is not predictive of response to endocrine therapy in advanced breast cancer

   Let n = 46 Tam n = 39 Total (n = 85)
ER level (Allred score)
negative ≤ 2 3 2 5
Low 3 0 0 0
  4 1 1 2
  5 2 1 3
  6 6 3 9
High 7 10 8 18
  8 21 19 40
N.A. (not assessable) 3 5 8
Total positive 40 32 72
PR level (Allred score)
negative ≤ 2 9 9 18
Low 3 3 1 4
  4 5 3 8
  5 4 5 9
  6 1 6 7
High 7 6 0 6
  8 14 12 26
N.A. (not assessable) 4 3 7
Total positive   33 27 60
COX-2 level (Allred score)
negative ≤ 2 13 11 24
Low 3 0 2 2
  4 5 4 9
  5 10 2 12
  6 7 6 13
High 7 5 7 12
  8 1 0 1
N.A. (not assessable) 5 7 12
Total positive   28 21 49
Aromatase level (Carcinoma cell SIP score)
negative 0 10 5 15
Low 1 3 3 6
  2 9 3 12
  3 2 3 5
  4 5 9 14
  6 8 5 13
  8 0 2 2
High 9 2 3 5
  12 2 1 3
N.A. (not assessable) 5 5 10
Total positive 30 30 60