Figure 2From: In situaromatase expression in primary tumor is associated with estrogen receptor expression but is not predictive of response to endocrine therapy in advanced breast cancer Time to progression (TTP) according to high, low and negative expression of COX-2 and Aromatase in primary tumor tissue for patients treated with either letrozole (black) or tamoxifen (grey). (A) TTP according to COX-2 expression: Letrozole treatment, COX-2 high, n = 6; COX-2 low, n = 22; COX-2 negative, n = 13. Tamoxifen treatment, COX-2 high, n = 7; COX-2 low, n = 14; COX-2 negative, n = 11. (B) TTP according to Aromatase expression: Letrozole treatment, Aromatase high, n = 4; Aromatase low, n = 27; Aromatase negative, n = 10. Tamoxifen treatment, Aromatase high, n = 4; Aromatase low, n = 25; Aromatase negative, n = 4.Back to article page