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Table 1 The cytotoxic effect of LfcinB and KW5 against FEMX and HT-29 cells.

From: The anticancer activity of lytic peptides is inhibited by heparan sulfate on the surface of the tumor cells

Peptides

FEMX

aIC50 (μM)

HT-29

IC50 (μM)

Ratio(IC50)HT-29 cells/FEMX cells

LfcinB

40 ± 7

148 ± 8

3.7

KW5

30 ± 3

55 ± 14

1.8

  1. aIC50 is the inhibitory concentration of the peptides where 50% of the cells are killed.
  2. Data are mean ± SEM (n = 5).
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BMC Cancer

ISSN: 1471-2407

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