Linkage disequilibrium across the NBN gene and neighbouring chromosomal region. Upper part shows linkage disequilibrium (LD) results (r2 and |D'|) obtained from the control genotypes data used in our study and their relative position along NBN sequence. In the bottom part of the figure are indicated r2 data from the International HapMap project (release 21a) for the genomic region encompassing NBN. The intensity of the box color is proportional to the strength of LD. r2 = 0 in white; 0 < r2 < 1 in shades of pink/red; r2 = 1 in bright red.