From: Fast simultaneous detection of K-RASmutations in colorectal cancer
 |  | mutation of codon 12 1st base | mutation of codon 13 2nd base | ||||||
---|---|---|---|---|---|---|---|---|---|
 |  | no | yes | total | p-value | no | yes | total | p-value |
Tumor size | <= 3 cm | 55 | 5 | 57 | 1 | 56 | 1 | 57 | 0.03 |
 | >3 cm | 160 | 8 | 168 |  | 149 | 19 | 168 |  |
Grade | Well | 4 | 0 | 4 | 0.749 | 4 | 0 | 4 | 0.416 |
 | Moderate | 171 | 9 | 180 |  | 161 | 19 | 180 |  |
 | Poor | 10 | 1 | 11 |  | 11 | 0 | 11 |  |
Lymph node metastasis | - | 107 | 2 | 109 | 0.048 | 101 | 8 | 109 | 0.621 |
 | + | 88 | 8 | 96 |  | 87 | 9 | 96 |  |
Stage | I, II | 76 | 0 | 76 | 0.121 | 70 | 6 | 76 | 0.782 |
 | III, IV | 76 | 4 | 80 |  | 72 | 8 | 80 |  |
Survival | <= 5 years | 114 | 9 | 123 | 0.023 | 109 | 14 | 123 | 0.162 |
 | >5 years | 104 | 1 | 105 |  | 99 | 6 | 105 |  |