Skip to main content

Table 2 Association of BNIP3 mRNA and protein expression with clinicopathological features in invasive breast cancer (n = 40).

From: Expression of BNIP3 in invasive breast cancer: correlations with the hypoxic response and clinicopathological features

 

BNIP3 mRNA

 

BNIP3 protein

 

Feature*

Low

High

p-value

Low

High

p-value

Lymph node status

      

   Negative

5

12

0.001

3

14

0.009

   Positive

19

4

 

15

9

 

MAI (2 mm 2 )

      

   1–12

9

9

0.335

4

14

0.027

   ≥ 13

15

7

 

13

9

 

ER

      

   Negative

7

6

0.733

5

8

1.000

   Positive

17

10

 

12

15

 

PR

      

   Negative

12

7

0.755

10

9

0.337

   Positive

12

9

 

7

14

 

Tumor size

      

   0–2 cm

7

6

0.733

3

10

0.103

   > 2 cm

17

10

 

14

13

 

Histological grade

      

   I/II

11

10

0.349

6

15

0.108

   III

13

6

 

12

8

 

Necrosis

      

   Negative

17

9

0.500

10

16

0.520

   Positive

7

7

 

7

7

 
  1. * MAI: mitotic activity index, ER: estrogen receptor, PR: progesterone receptor.
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us