Differential baseline and response profile to IFN-γ gene transduction of IL-6/IL-6 receptor-α secretion discriminate primary tumors versus bone marrow metastases of nasopharyngeal carcinomas in culture

Table 3 Comparative production of IL-6/IL-6Rα by P-NPC and metastasis-derived NPC cell lines at day 3 in vitro culture

Variable	P-NPC cell lines (n = 5)	Metastasis-derived NPC cell lines (n = 3)	p value^#
IL-6 (pg/ml)	60.8 ± 50.7 ^†	787.7 ± 522.9	0.025
IL-6Rα (pg/ml)	609.5 ± 252.8	124.6 ± 90.1	0.025

^† Results were expressed as mean ± SD. p values were calculated by using ^#Mann-Whitney U test for comparison of IL-6 and IL-6Rα production in culture.

ISSN: 1471-2407